Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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466
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480
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466
Tocris Bioscience™ BI 78D3
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 883065-90-5 Molecular Formula: C13H9N5O5S2
| CAS | 883065-90-5 |
|---|---|
| Molecular Formula | C13H9N5O5S2 |
467
Tocris Bioscience™ Tomoxetine hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 82248-59-7 Molecular Formula: C17H22ClNO
| CAS | 82248-59-7 |
|---|---|
| Molecular Formula | C17H22ClNO |
469
Tocris Bioscience™ Pomalidomide 4'-PEG2-amine
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Cereblon ligand with PEG linker and terminal amine for onward chemistry
470
Tocris Bioscience™ EO 1428
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CAS: 321351-00-2 Molecular Formula: C20H16BrClN2O
| CAS | 321351-00-2 |
|---|---|
| Molecular Formula | C20H16BrClN2O |
471
Tocris Bioscience™ (-)-Xestospongin C
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CAS: 88903-69-9 Molecular Formula: C28H50N2O2
| CAS | 88903-69-9 |
|---|---|
| Molecular Formula | C28H50N2O2 |
472
Tocris Bioscience™ MLN 4924
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective NEDD8 activating enzyme (NAE) inhibitor; cell permeable
| Target | NEDD8 Activating Enzyme E1) |
|---|---|
| CAS | 905579-51-3 |
| Purity | 0.98 |
| Chemical Name or Material | [(1 S,2 S,4 R)-4-[4-[[(1 S)-2,3-Dihydro-1 H-inden-1-yl]amino]-7 H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamic acid ester |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H25N5O4S |
473
Tocris Bioscience™ Idasanutlin
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Potent MDM2 inhibitor; inhibits MDM2-p53 interaction
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C31H29Cl2F2N3O4 |
| Formula Weight | 616.49 |
474
475
Tocris Bioscience™ TAK 165
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective ErbB2 inhibitor
| Inhibitors | TAK 165 |
|---|---|
| Product Type | TAK 165 |
| Molecular Weight (g/mol) | 468.47 |
| Purity | >99% |
476
Tocris Bioscience™ uPSEM 792 hydrochloride
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Highly potent PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant
| Target | Pharmacologically Selective Effector Molecules/PSEM |
|---|---|
| CAS | 2341841-08-3 |
| Purity | 98% |
| Chemical Name or Material | 1-Methyl-7,8,9,10-tetrahydro-1 H-6,10-methanoazepino[4,5-g]quinoxalin-2(6 H)-one hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H15N3O.HCl |
| Formula Weight | 277.75 |
477
Tocris Bioscience™ Imipramine hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment
478
Tocris Bioscience™ BMS 265246, >97%
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 582315-72-8 Molecular Formula: C18H17F2N3O2
| CAS | 582315-72-8 |
|---|---|
| Molecular Formula | C18H17F2N3O2 |
479
Tocris Bioscience™ Picropodophyllotoxin
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 477-47-4 Molecular Formula: C22H22O8
| CAS | 477-47-4 |
|---|---|
| Molecular Formula | C22H22O8 |
480
Tocris Bioscience™ TC-S 7005
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1082739-92-1 Molecular Formula: C21H17N3O3
| CAS | 1082739-92-1 |
|---|---|
| Molecular Formula | C21H17N3O3 |